FORD, DANIEL JAMES,HORSLEY, HELEN TRACEY,REUBERSON, JAMES THOMAS
申请号：
CA2998802
公开号：
CA2998802A1
申请日:
2016.09.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A series of substituted pyrazolo[1,5-a]pyrimidine and pyrazolo[1,5-a][1,3,5]- triazine derivatives of formula (I), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase ???ß (?I4????ß) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders viral diseases and malaria and organ and cell transplant rejection.
