PROBLEM TO BE SOLVED: To provide a composition of an oncology-related polynucleotide, an oncology-related primary transcript, and an oncology-related mRNA molecule, and a method for preparing, producing, and therapeutically using them. A method of treating a disease, disorder, and / or condition of a subject in need of treatment of the disease, disorder, and / or condition by increasing the level of the oncology-related polypeptide of interest. , A method comprising administering to said subject an isolated polynucleotide encoding the said oncology-related polypeptide. [Selection diagram] None【課題】腫瘍学関連ポリヌクレオチド、腫瘍学関連一次転写物、及び腫瘍学関連mmRNA分子の組成物、並びに、これらの調製、製造、及び治療的使用の方法の提供。【解決手段】目的の腫瘍学関連ポリペプチドのレベルを高めることにより、疾患、障害、及び/又は状態の治療を必要とする対象の前記疾患、障害、及び/又は状態を治療する方法であって、前記腫瘍学関連ポリペプチドをコードする単離ポリヌクレオチドを前記対象に投与することを含む方法。【選択図】なし