GERON CORPORATION;THE REGENTS OF THE UNIVERSITY OF COLORADO
发明人:
THOMAS R. CECH,JOACHIM LINGNER,TORU M. NAKAMURA,KAREN B. CHAPMAN,GREGG B. MORIN,CALVIN B. HARLEY,WILLIAM H. ANDREWS
申请号:
US14984959
公开号:
US20160263203A1
申请日:
2015.12.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.