炎性體活性化抑制劑

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专利权人:

KRACIE HOLDINGS, LTD.;客樂諧控股株式會社

发明人:

WATANABE Shimpei,ARAI Ayako,TAKAJO Yuichi,INAMASU Satoshi,YOMODA Satoshi,OHNO Akiko,KITAHARA Yuko,KANATANI Taisaku,YOMODA Satoshi,與茂田敏,OHNO Akiko,大野晶子,KITAHARA Yuko,北原裕子,KANATANI Taisaku,金谷太作

申请号：

HK18116653

公开号：

HK1257568A1

申请日:

2018.12.27

申请国别(地区):

HK

年份:

2019

代理人:

摘要：

To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1² released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has aneffect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/