INHIBITEUR DE L'ACTIVATION DES INFLAMMASOMES

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专利权人:

Kracie Holdings; Ltd

发明人:

WATANABE, Shimpei,ARAI, Ayako,TAKAJO, Yuichi,INAMASU, Satoshi,YOMODA, Satoshi,OHNO, Akiko,KITAHARA, Yuko,KANATANI, Taisaku

申请号：

EP17750307

公开号：

EP3415146A4

申请日:

2017.02.08

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1² released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has aneffect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/