Provided is a use of a composition containing a ferrous amino acid chelate for the preparation of pharmaceuticals used in diabetes improvement. The pharmaceuticals comprise an effective amount of the composition containing the ferrous amino acid chelate and pharmaceutically acceptable carriers to improve diabetes. The amino acid is able to be chelated with the ferrous iron in a chelated state stably as passing through a stomach. The composition containing the ferrous amino acid chelate can effectively lower blood glucose and improve insulin sensitivity. The pharmaceuticals prepared by the composition containing the ferrous amino acid chelate have effect on diabetes improvement.