Pierre-Francois Berne,Francis Blanche,Hervé Bouchard,Béatrice Cameron,Tarik Dabdoubi,Stéphanie Decary,Paul Ferrari,Alexey Rak
申请号:
US14716377
公开号:
US09617345B2
申请日:
2015.05.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention discloses antibodies which bind human and Macaca fascicularis CEACAM5 proteins, as well as isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies. The invention also discloses immunoconjugates comprising said antibodies conjugated or linked to a growth-inhibitory agent, and to pharmaceutical compositions comprising antibodies, or immunoconjugates of the invention. The antibodies or immunoconjugates of the invention are used for the treatment of cancer or for diagnostic purposes.