Pierre-Francois Berne,Francis Blanche,Hervé Bouchard,Béatrice Cameron,Tarik Dabdoubi,Stéphanie Decary,Paul Ferrari,Alexey Rak
申请号：
US15446465
公开号：
US10457739B2
申请日:
2017.03.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Antibodies are provided which bind human and Macaca fascicularis CEACAM5 proteins, as well as isolated nucleic acids, vectors and host cells comprising a sequence encoding the antibodies. Also provided are immunoconjugates comprising the antibodies conjugated or linked to a growth-inhibitory agent, and to pharmaceutical compositions comprising the antibodies, or immunoconjugates of the invention. The antibodies or immunoconjugates are used for the treatment of cancer or for diagnostic purposes.
