Pierre-Francois BERNE,Francis BLANCHE,Hervé BOUCHARD,Béatrice CAMERON,Tarik DABDOUBI,Stéphanie DECARY,Paul FERRARI,Alexey RAK
申请号:
US16558939
公开号:
US20200102401A1
申请日:
2019.09.03
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention discloses antibodies which bind human and Macaca fascicularis CEACAM5 proteins, as well as isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies. The invention also discloses immunoconjugates comprising said antibodies conjugated or linked to a growth-inhibitory agent, and to pharmaceutical compositions comprising antibodies, or immunoconjugates of the invention. The antibodies or immunoconjugates of the invention are used for the treatment of cancer or for diagnostic purposes.