Board Of Regents Of the University Of Texas System
发明人:
GEORGIOU, George,STONE, Everett,BLAZECK, John
申请号：
EP17760774
公开号：
EP3423483A4
申请日:
2017.03.02
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.
