George GEORGIOU,Everett STONE,John BLAZECK,Christos KARAMITROS
申请号：
US16385562
公开号：
US20190350975A1
申请日:
2019.04.16
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.
