Enzyme-mediated depletion of adenosine and/or methylthioadenosine

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专利权人:

The University of Texas System;Board of Regents

发明人:

STONE, Everett,GJUKA, Donjeta

申请号：

AU2018393093

公开号：

AU2018393093A1

申请日:

2018.12.20

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

Methods and compositions related to the engineering of a protein with MTA/ADO- degrading enzyme activity are described. For example, in certain aspects there may be disclosed an MTase capable of degrading MTA/ADO. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer or SCID with an MTase using the disclosed proteins or nucleic acids.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/