George Georgiou,Everett Stone,Nicholas Marshall,John Blazeck,Wei-Cheng Lu
申请号：
US14839293
公开号：
US09975959B2
申请日:
2015.08.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.
