The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.本揭示提供不同治療性細胞群體，其形成可用於造血幹細胞/祖細胞移植之醫藥組合物。舉例而言，本揭示提供治療性細胞群體，其包含造血幹細胞/祖細胞、記憶性T細胞、調節性T細胞之富集群體，且其中該細胞群體空乏初始習用αβ-T細胞。本揭示進一步提供使用該治療性細胞群體之治療方法。在其他實施例中，本揭示提供產生治療性細胞群體之方法。
