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COMPOSITIONS AND METHODS OF HEMATOPOIETIC STEM CELL TRANSPLANTS
专利权人:
Orca Biosystems; Inc.
发明人:
Ivan K. Dimov,Nathaniel Fernhoff,Kevin Sheehan
申请号:
US16388095
公开号:
US20190298773A1
申请日:
2019.04.18
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.
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