ENA nucleic acid pharmaceuticals capable of modifying splicing of mRNA precursors

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专利权人:

Makoto Koizumi;Masafumi Matsuo;Yasuhiro Takeshima

发明人:

Masafumi Matsuo,Yasuhiro Takeshima,Makoto Koizumi

申请号：

US13673466

公开号：

US09657049B2

申请日:

2012.11.09

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.

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