The adaptor associated kinase 1 (AAK1) inhibitor 3-methyloxetan-3-yl-4-(3-(2-methoxypyridin-3-yl)pyrazol o[1,5-a]pyrimidin-5-yl)piperazine-1-carboxylate: and pharmaceutically acceptable salts and solid forms thereof are disclosed. Compositions comprising the compound and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by AAK1 activity are also disclosed.本文揭示了一種銜接子關聯激酶1(AAK1)抑制劑，亦即3-甲基氧雜環丁-3-基-4-(3-(2-甲氧基吡啶-3-基)吡唑并[1,5-a]嘧啶-5-基)哌嗪-1-甲酸酯：及其醫藥學上可接受的鹽類與固體形式。亦揭示了包含該化合物之組成物，以及將該化合物及包含該化合物之組成物用於治療、管理及/或預防由AAK1活性介導的疾病及病症的方法。
