Claim 1: a compound of formula (1), wherein X is selected from h, F, Cl, Br, I, cyanogen, nitrate, Ethiopia, cyclopentyl, methyl, ethyl, isopropyl, ethylene and methoxy groups, and is one to four residues independently selected from h, F, Cl, Br, I, cn, oh, nitro, low tar and cyclopentyl compounds, Low calcium, low calcium, cyclopentadiene, low asphalt； Z is low oxygen； R1 is selected from the following asphalt, low medium, low medium, alternative, arilo, alternative, heterogeneous, alternative heteromorphic, heterocyclic, alternative, cyclopentyl compounds,1. Cyclopentyl substitutes, cyclopentyl substitutes and cyclopentyl substitutes selected from formula group (2)； R 2 is a substitute；(3) And (4)；W is f, CL or br； V is h or F； R3 is selected from the hydrogen, low tar and substituted low tar groups； r830808 is selected from the remaining formula groups (5) and (6)；R83099 is composed of - (oc832222； ch8322)； - 8345； - (oc832222)； ch8345； - oc832323) of the following asphalts, substituted lower asphalts, heterocycles, substituted heterocycles, cyclopentanediol, substituted cyclopentanediol, natural and unnatural amino acids；-(NCH 8322；) - 8345； - Oh, - (nch8322； - ch832222) - 8345； - och 8323y - (och 83222；) - op (o) (or8310a) 8322；N is 3-60； r83100s is hydrogen or benzene； or salt or ester that can be accepted from medicine；Reivindicación 1: Un compuesto de la fórmula (1) en la que: X se elige entre el grupo formado por H, F, Cl, Br, I, ciano, nitro, etinilo, ciclopropilo, metilo, etilo, isopropilo, vinilo y metoxi； Y es de uno a cuatro restos elegidos con independencia entre el grupo formado por H, F, Cl, Br, I, CN, OH, nitro, alquilo inferior, cicloalquilo, alcoxi inferior, alquenilo inferior, cicloalquenilo, alquinilo inferior； Z es alcoxi inferior； R¹ se elige entre el grupo formado por alquilo inferior, alquilo inferior sustituido, alquenilo inferior, alquenilo inferior sustituido, arilo, arilo sustituido, heteroarilo, heteroarilo sustituido, heterociclo, h
