Cyclopenta[d]pyrimidines hydroxylées et méthoxylées utilisées en tant qu'inhibiteurs de la protéine kinase AKT

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专利权人:

Array Biopharma, Inc.;Genentech, Inc.

发明人:

申请号：

EP11166125.2

公开号：

EP2402325A2

申请日:

2007.07.05

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I:Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. Further provided are method of synthesis of these compounds and intermediates in the synthesis process.

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中国工程科技知识中心

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