Ltd.;Guizhou Bailing Enterprise Group Pharmaceutical Co.
发明人:
申请号:
EP16782564.5
公开号:
EP3287459A1
申请日:
2016.04.12
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The Invention relates to the field of chemical medicines, and particularly to a purinyl-N-hydroxyl pyrimidine formamide derivative, preparation methods and uses thereof. The Invention provides a purinyl-N-hydroxyl pyrimidine formamide derivative with a structure shown in Formula I. The Invention also provides preparation methods and uses of said purinyl-N-hydroxyl pyrimidine formamide derivative. The purinyl-N-hydroxyl pyrimidine formamide derivative provided in the Invention can be not only a kinase inhibitor with PI3K and HDAC difunctional targets, but also a kinase inhibitor with single PI3K or HDAC functional target, thus providing a new choice for preparing multi-target inhibitors.