PROCEDES D'UTILISATION D'INHIBITEURS DE L'ADENOSINE EXTRACELLULAIRE ET D'INHIBITEURS DE RECEPTEUR DE L'ADENOSINE AUX FINS D'AMELIORATION DE REPONSE IMMUNE ET D'INFLAMMATION
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
SITKOVSKY, MICHAIL V.,OHTA, AKIO
申请号:
CA2470104
公开号:
CA2470104C
申请日:
2002.11.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
A method is provided herein to increase an immune response to an antigen. Themethod includes administering an agent that inhibits extracellular adenosineor inhibits adenosine receptors. Also disclosed are methods to increase theefficacy of a vaccine and to increase an immune response to a tumor antigen orimmune cell-mediated tumor destruction.