The Government of the United States of America as represented by the Secretary of the Department of
发明人:
Michail V. Sitkovsky,Akio Ohta
申请号:
US16391423
公开号:
US20190262449A1
申请日:
2019.04.23
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increase an immune response to a tumor antigen or immune cell-mediated tumor destruction.