Method of treating cancer comprising administering 2 - amino - 4 - methyl - ethyl - 4 - 6 - (1h pyrazole - 5 - il) pirido [2,3-d] pyrimidine 7 (8h) - one and N - ((S) - (2,3-dihydroxypropyl) - 3 - (2 - fluoro - 4 - Iodine - phenylamino) isonicotinamide； Pharmaceutical composition； use a Combination to treat cancer as cancer Lung, Triple Negative Breast Cancer, among others.

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专利权人:

SANOFI;MERCK PATENT GMBH

发明人:

OGDEN, JANET ANNE MEURER,LAGER, JOANNE,HSU, KARL

申请号：

CL2014002668

公开号：

CL2014002668A1

申请日:

2014.10.03

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

Methods of treating patients with cancer are provided, wherein the methods comprise administering to the patient an effective amount of a MEK inhibitor and an effective amount of a PI3K inhibitor. Compositions in which the MEK and PI3K inhibitors are combined also are described.MÉTODO DE TRATAMIENTO DEL CÁNCER QUE COMPRENDE ADMINISTRAR 2-AMINO-8-ETIL-4-METIL-6-(1H-PIRAZOL-5-IL)PIRIDO[2,3-D]PIRIMIDIN-7(8H)-ONA Y N-((S)-2,3-DIHIDROXIPROPIL)-3-(2-FLUORO-4-YODO-FENILAMINO)ISONICOTINAMIDA； COMPOSICION FARMACEUTICA； USO DE UNA COMBINACION PARA TRATAR CANCER TAL COMO CANCER DE PULMON, CANCER DE MAMA TRIPLE NEGATIVO, ENTRE OTROS.

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中国工程科技知识中心

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http://www.ckcest.cn/home/