Pharmaceutical composition comprising: (1) n - [(2S) - 2,3-dihydroxypropyl] - 3 - (2-fluoro-4 - iodoanilino) pyridin - 4 - carboxamide and 2a) 2 - amino - N - [3 - [[3 - (2 - Chloro - 5 - metoxianilin) quinoxalin - 2 - yl] sulfamoyl] phenyl] - 2 - metilpropanamida or 2b) 2 - amino - 4 - methyl - ethyl - 4 - 6 - (1h pyrazole - 5 - il) pirido [2,3-d] pyrimidin-7-one； Use for the treatment of cancer； a Kit

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专利权人:

SANOFI;MERCK PATENT GMBH

发明人:

DEBUSSCHE, LAURENT,MA, JIANGUO,MCMILLAN, STUART,OGDEN, JANET ANNE MEURER,VINCENT, LOIC,GARCIA-ESCHEVERRIA, CARLOS

申请号：

CL2013001643

公开号：

CL2013001643A1

申请日:

2013.06.07

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

Methods of treating patients with cancer are provided, wherein the methods comprise administering to the patient an effective amount of a MEK inhibitor and an effective amount of a PI3K inhibitor. Compositions in which the MEK and PI3K inhibitors are combined also are described.COMPOSICION FARMACEUTICA

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