SCHENK, Dale, B.,SEUBERT, Peter, A.,WALL, Jonathan,SALDANHA, Jose
申请号:
HUE08867535
公开号:
HUE025560T2
申请日:
2008.12.29
申请国别(地区):
HU
年份:
2016
代理人:
摘要:
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.