The present invention relates to a seedpod ofNelumbonuciferaThe present invention relates to a pharmaceutical composition and a health functional food for preventing or treating thrombosis which contains an ethanol extract as an active ingredient and more specifically to a pharmaceutical composition and a health functional food for preventing or treating thrombosis, To a pharmaceutical composition for preventing or treating / improving thrombosis through inhibition of strong platelet aggregation and inhibition of blood coagulation containing water as an effective ingredient and a health functional food. The pharmaceutical composition for the prevention or treatment of thrombosis according to the present invention and the lectin ethanol extract as an active ingredient of the health functional food inhibit the coagulation inhibition effect of platelets which inhibits the thrombogenesis-And exhibits excellent hemostatic activity against human erythrocytes, exhibits excellent thermal stability, exhibits an acidic condition of pH 2 and a loss of blood coagulation factor inhibitory effect and thrombogenic enzyme-inhibiting effect even in plasma It is expected that the composition can be used as a pharmaceutical composition and a health functional food for prevention and treatment / improvement of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation and the above active ingredient can be used as an extract, powder, Etc., so that it can be prepared in a form that can be taken at any time. It is a very useful invention in the pharmaceutical industry and food industry because of its excellent effect.본 발명은 연자방(Seedpod of Nelumbonucifera) 에탄올 추출물을 유효성분으로 함유하는 혈전증(thrombosis)의 예방 또는 치료용 약학적 조성물 및 건강 기능 식품에 관한 것으로서, 보다 구체적으로는, 연자방 에탄올 추출물, 상기 추출물의 유기 용매 분획물 또는 분획 후의 물 잔류물을 유효성분으로 함유하는 강력한 혈소판 응집 저해 및 혈액 응고 저해를 통한 혈전증의 예방 또는 치료/개선용 약학적 조성물 및 건강 기능 식품에 관한 것이다. 본 발명의 혈전증의 예방 또는 치료용 약학적 조성물 및 건강 기능 식품의 유효성분으로서의 연자방 에탄올 추출물은 혈전 생성 관련 효소 및