The present invention relates to a combination comprising compounds of formula (I):wherein R1 to R3, A, X and n are as defined herein, and an additional active agent. The present invention also relates pharmaceutical compositions comprising these combinations, and methods of using these combinations to treat various diseases and disorders.本發明係關於一種組合,其包括式(I)化合物:其中R1至R3、A、X及n係如本文中所定義;及其他活性劑。本發明亦係關於包括該等組合之醫藥組合物及使用該等組合治療各種疾病及病症之方法。