表皮生長因子受體抑制劑农业专利-农业学术服务平台

发明人:: ZAVIALOV, KIRILL VADIMOVICH,扎维亚拉夫　吉利尔　瓦迪莫维奇,扎維亞拉夫　吉利爾　瓦迪莫維奇,GORBUNOVA, SVETLANA LEONIDOVNA,果尔布诺娃　斯韦特兰娜　列昂尼多夫纳,果爾布諾娃　斯韋特蘭娜　列昂尼多夫納,SHEKHAUTSOU, ARTSIOM EVGENIEVICH,什卡乌苏　阿尔西姆　叶夫根尼维奇,什卡烏蘇　阿爾西姆　葉夫根尼維奇,KASA

摘要：: The present group of inventions relates to novel compounds having formula (I), and to the salts, solvates or stereoisomers thereof, as well as to a pharmaceutical composition, a method of inhibiting the biological activity of epidermal growth factor receptor (EGFR), a method of treating diseases or disorders mediated by EGFR activity, and the use of the claimed compounds or the aforementioned composition for treating a disease or a disorder mediated by EGFR activity.發明涉及式I所示的新化合物：或其藥學上可接受的鹽、溶劑合物或立體異構體，以及含本發明化合物的藥物組合物，抑制EGFR生物活性的方法，治療由ЕGFR活化所介導的疾病或病症的方法，和本發明化合物或藥物組合物用於治療由ЕGFR活化所介導的疾病或病症的用途。