Method for Treatment of Dysfunction of neurotransmission and other States associated with the activity of mglur4en involves use of Derivatives of pyrazole Heterocyclic compounds with other Heterocyclic Compounds； condensate； compositions containing same and use in the treatment of Neurological dysfunction.
CONN P. JEFREY,LINDSLEY W CRAIG,HOPKINS R COREY,NISWENDER M COLLEEN,GOGLIOTTI D ROCCO.,SALOVICH M JAMES,ENGERS W DARREN,CHEUNG YIU-YIN
申请号：
CL2012002225
公开号：
CL2012002225A1
申请日:
2012.08.10
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4)； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.COMPUESTOS DERIVADOS DE PIRAZOLOPIRIDINA, PIRAZOLOPIRAZINA, PIRAZOLOPIRIMIDINA, PIRAZOLOTIOFENO, PIRAZOLOTIAZOL； COMPOSICION FARMACEUTICA QUE LOS COMPRENDE； METODO DE PREPARACION DE UN MEDICAMENTO； Y USO DE LOS COMPUESTOS EN EL TRATAMIENTO DE UNA DISFUNCION NEUROLOGICA.
