DRAGHIA-AKLI, RUXANDRA,PRIGGE, JON,SARDESAI, NIRANJAN Y.,WEINER, DAVID B.,HIRAO, LAUREN A.
申请号:
CA2725383
公开号:
CA2725383C
申请日:
2009.05.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to DNA vaccines that are capable of generating aprotective immune response inmammals against a pox virus, and comprises at least one DNA plasmid capable ofexpressing a plurality of VACV MV antigens,and at least one DNA plasmid capable of expressing a plurality of VACV EVantigens. Also, the present invention relates tomethods of inducing a protective immune response in a mammal to pox virus,including a neutralizing antibody response,com-prising: injecting into tissue of said mammal said DNA vaccine.