JAESCHKE GEORG,LINDEMANN LOTHAR,STADLER HEINZ,VIEIRA ERIC
申请号：
NZ70184913
公开号：
NZ701849A
申请日:
2013.07.12
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
The present invention relates to ethynyl derivatives of formula (I) wherein R1 is phenyl, which is optionally substituted by 1-2 halogen atoms； selected from fluorine or chlorine； or to a pharmaceutically acceptable acid addition salt in enantiomerically pure form. It has been found that the compounds of general formula (I) are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
