Philip Yan;Susan K. Paulson;Rebecca S. Hoffman;George R. Granneman;Elliot K. Chartash;Lori K. Taylor;Joanna Z. Peng
发明人:
Rebecca S. Hoffman,Elliot K. Chartash,Lori K. Taylor,George R. Granneman,Philip Yan,Susan K. Paulson,Joanna Z. Peng
申请号:
US13433205
公开号:
US20130122011A1
申请日:
2012.03.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.