Rebecca S. Hoffman,Elliot Keith Chartash,Lori K. Taylor,George Richard Granneman,Philip Yan,Susan K Paulson,Joanna Z. Peng
申请号:
US14745092
公开号:
US20170044249A1
申请日:
2015.06.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.