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MULTIPLE-VARIABLE DOSE REGIMEN FOR TREATING TNFALPHA-RELATED DISORDERS
专利权人:
AbbVie Biotechnology Ltd.
发明人:
Rebecca S. Hoffman,Elliot Keith Chartash,Lori K. Taylor,George Richard Granneman,Phillip Yan
申请号:
US14229602
公开号:
US20140248275A1
申请日:
2014.03.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
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