Multimerization of recombinant protein by fusion to a sequence from lamprey

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专利权人:

Sanofi Pasteur

发明人:

Régis Sodoyer,Isabelle Legastelois

申请号：

US15536726

公开号：

US10118951B2

申请日:

2015.12.18

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to polymerized recombinant proteins, to recombinant nucleic acids coding for the polymerized recombinant proteins, to expression cassettes comprising the recombinant nucleic acids, to host cells transformed by the expression cassettes and to a method for multimerizing a recombinant protein. The polymerized proteins of the invention may be used in pharmaceutical or immunogenic compositions. In particular, the recombinant proteins may be antigens, antibodies or scaffolds. In particular, the polymerized recombinant protein may be an influenza haemagglutinin.

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