A safety transfusion catheter includes a flexible retention tube fitted over a metal guiding needle. The flexible retention tube is provided with a needle handle connected with it. The angle between the end of the flexible retention tube and its longitudinal axis or longitudinal tube wall is less than 90.degree. The cross section of the needle handle has an outer contour line of a closed curve formed with a curve intersecting a beeline. A further safety transfusion catheter includes a flexible retention tube fitted over a metal guiding needle, a transfusion connecting tube in fluid communication with flexible retention tube and a rubber casing cap at the end of the flexible retention tube. The transfusion connecting tube and flexible retention tube form a T-shaped or an oblique Y-shaped structure.