DEVRIES, VERN GORDON,CLAUS, THOMAS HARRISON,FLOYD JR , MIDDLETON BRAWNER,AYRAL-KALOUSTIAN, SEMIRAMIS
申请号:
EP19890110990
公开号:
EP0354323(A2)
申请日:
1989.06.16
申请国别(地区):
欧洲专利局
年份:
1990
代理人:
摘要:
Phosphates are disclosed which stimulate the enzyme fructose-1,6-bisphosphatase and inhibit the enzyme 6-phosphofructo-1-kinase, thereby lowering glucose levels in mammals. These phosphates may thus be used to treat hyperglycemia and/or diabetes. Processes for the synthesis of the phosphates are also disclosed.