Federalnoe gosudarstvennoe avtonomnoe uchrezhdenie "Mezhotraslevoj nauchno-tekhnicheskij kompleks "Mikrokhirurgiya glaza" imeni akademika S.N. Fedorova" Ministerstva zdravookhraneniya Rossijskoj Feder
发明人:
Iojleva Elena Eduardovna (RU),Иойлева Елена Эдуардовна (RU),Krivosheeva Mariya Sergeevna (RU),Кривошеева Мария Сергеевна (RU),Bondarenko Mariya Alekseevna (RU),Бондаренко Мария Алексеевна (RU)
申请号：
RU2018111945
公开号：
RU0002674883C1
申请日:
2018.04.03
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to ophthalmology and radiation diagnosis, and can be used to diagnose atrophy of the optic nerve (ONA) in patients with multiple sclerosis (MS). Area of the optic nerve disk and the peripapillary area are scanned in a circle with a diameter of 3.46 mm using optical coherence tomography. Measure the thickness of the middle layer of nerve fibers of the retina according to the protocol Optic Disc Cube 200×200 and the macular area of the ellipse. Major axis of the ellipse is horizontal and is equal to 3.46 mm, the smaller axis is equal to 2.8 mm. Ellipse is divided into 6 equal sectors. Measure the thickness of the complex of retinal ganglion cells (RGC) with an internal plexiform layer (IPL) according to the Ganglion Cell Analysis protocol: Macular Cube 512×128. If the average thickness of the middle layer of the nerve fibers of the retina is less than 62 microns, the average thickness of the RGC complex with IPL is less than 52 microns, the average thickness of the upper sector of the RGC complex with IPL is less than 51 microns, the average thickness of the lower sector of the RGC complex with IPL is less than 50 microns, then ONA is diagnosed in patients with MS.EFFECT: method provides reliable diagnostics of ONA in MS by measuring the thickness of the middle layer of nerve fibers of the retina and the average thickness of the RGC complex with IPL by means of optical coherent tomography.1 cl, 2 exИзобретение относится к медицине, а именно к офтальмологии и лучевой диагностике, и может быть использовано для диагностики атрофии зрительного нерва (АЗН) у пациентов с рассеянным склерозом (PC). Сканируют область диска зрительного нерва и перипапиллярную область по кругу диаметром 3,46 мм методом оптической когерентной томографии. Измеряют толщину среднего слоя нервных волокон сетчатки по протоколу Optic Disc Cube 200×200 и макулярную область по эллипсу. Большая ось эллипса расположена горизонтально и равна
