HSIEH, MING FA,谢明发,謝明發,FANG, CHIH HSIANG,方志翔,方志翔,JIANG, CHO PEI,江卓培,江卓培,LEE, HUNG MAAN,李宏满,李宏滿
申请号:
TW104144217
公开号:
TW201636054A
申请日:
2015.12.29
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
This invention provides a composite-type scaffold system and used to promoting the regeneration of cartilage and/or bone tissues, and thus providing a potential means to treat osteoarthritis. The present composite-type scaffold system comprises a scaffold, which is made of a PEG-PCL polymer condensed linked to a RGD peptide, and prepared with a hydroxyapatite, and a GMHA hydrogel containing a growth factor therein.本發明係為一種複合型支架系統,該複合型支架系統可促進軟骨及/或硬骨組織的再生,因此能有效治療骨關節炎。本發明之支架系統包含一支架,其係由一與RGD胜肽縮合連接之聚乙二醇-聚己內酯聚合物,以及由一氫氧基磷灰石所製成,並一包含生長因子的甲基丙烯酸環氧丙酯-玻尿酸水凝膠。