PROBLEM TO BE SOLVED: To provide a compound having an excellent angiogenesis inhibitory action useful as a therapeutic agent for a disease associated with angiogenesis.SOLUTION: The useful compound is an oxadiazole derivative or a thiadiazole derivative each represented by formula (I) or a salt thereof. In the formula, ring A represents a benzene ring or a heterocycle Ra represents a hydrogen atom, a halogen atom or the like ring B represents a heterocycle containing nitrogen ring C represents a benzene ring or a heterocycle containing nitrogen X and Y each represents an oxygen atom or a sulfur atom R1 represents a hydrogen atom, a halogen atom, an amino group, a cycloalkylamino group or a non-aromatic heterocyclic group and R2 and R2 each represents a hydrogen atom, a halogen atom, an alkyl group or the like.COPYRIGHT: (C)2009,JPO&INPIT【課題】優れた血管新生阻害作用を有し、血管新生が関与する疾患の治療剤として有用な化合物の提供。【解決手段】式(I)で表されるオキサジアゾール誘導体およびチアジアゾール誘導体又はその塩。式中、環Aはベンゼン環、ヘテロ環;Raは水素原子、ハロゲン原子等;環Bは含窒素ヘテロ環;環Cはベンゼン環、含窒素ヘテロ環;XとYはO又はS原子;R1は水素原子、ハロゲン原子、アミノ基、シクロアルキルアミノ基、又は非芳香族複素環基;R2とR2’はH、ハロゲン原子、アルキル基等を示す。【選択図】なし
