Zhaochun Chen,Stephen Leppla,Mahtab Moayeri,Suzanne U. Emerson,Robert H. Purcell
申请号：
US11793735
公开号：
US08685396B2
申请日:
2005.12.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to monoclonal antibodies that bind or neutralize anthrax protective antigen (PA) toxin. The invention provides such antibodies, fragments of such antibodies retaining anthrax PA toxin-binding ability, fully human or humanized antibodies retaining anthrax PA toxin-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention.
