A clamp apparatus for selectively occluding a resilient tube to prevent freeflow offluid in the tube comprises a base member to which the resilient IV tube isattached or throughwhich it passes, and a slide clamp that slides relative to the base member andthe tube. Anaperture in the slide clamp has a relatively open hole at one end, throughwhich the tubepasses when the slide clamp is an open position, allowing fluid to flowthrough the tube. Theaperture has a relatively constricted slot at the other end, through which thetube passes whenthe slide clamp is in the occluding position, preventing fluid flow throughthe tube. Theapparatus serves to automatically and positively occlude an IV tube andmaintain the IV tubein an occluded state.