Aminoalquilpirimidina refers to compounds of formula (i) wherein R1 is H or alkyl (c1-c4) R2 is acetidinilo, pirrolidinilo, piperidinilo acepanilo or optionally substituted alkyl (c1-c4) R1 and R2 with the N Atom to which they are United to form a Heterocyclic Group monocicl From 4 to 7 members,Bridged bicyclic 7 to 8 members or FUSED bicyclic 8 to 12 members optionally substituted R3 is H or alkyl (C1 C8 alkyl R4 (C1) is optionally substituted by halogen - C8), (ISBN C10 cycloalkyl) alkyl, arylalkyl (C0 (C0 - C4) - C4), between other R5 is H or alkyl (C8 - C1) n is 1 or 2.Preferred compounds are: 4 - ((ciclopropilmetilamino) methyl) - 6 - (3 - (methylamino) acetidin IL - 1 - 2 - pyrimidin-2-yl) - Amine 4 - ((2 - adamantilamino) methyl) - 6 - (3 - (methylamino) acetidin IL - 1 - 2 - pyrimidin-2-yl) - Amine 4 - (((- 2.2 - dietilciclopropil) methylamino) methyl) - 6 - (3 - (methylamino) acetidin IL - 1 - 2 - pyrimidin-2-yl) - Amine among others. It also relates to a preparation method and a Pharmaceutical composition.These compounds are antagonists of Histamine H4 Receptor being useful in the treatment of Asthma, allergic rhinitis, dermatitis, psoriasis, cutaneous lupusSE REFIERE A COMPUESTOS DERIVADOS DE AMINOALQUILPIRIMIDINA DE FORMULA (I) DONDE R1 ES H O ALQUILO(C1-C4) R2 ES ACETIDINILO, PIRROLIDINILO, PIPERIDINILO O ACEPANILO OPCIONALMENTE SUSTITUIDOS CON ALQUILO(C1-C4) O R1 Y R2 JUNTO AL ATOMO DE N AL QUE ESTAN UNIDOS FORMAN UN GRUPO HETEROCICLICO MONOCICLICO DE 4 A 7 MIEMBROS, BICICLICOS PUENTEADOS DE 7 A 8 MIEMBROS O BICICLICOS FUSIONADOS DE 8 A 12 MIEMBROS OPCIONALMENTE SUSTITUIDO R3 ES H O ALQUILO(C1-C8) R4 ES ALQUILO(C1-C8) OPCIONALMENTE SUSTITUIDO CON HALOGENO, CICLOALQUILO(C3-C10)-ALQUILO(C0-C4), ARILALQUILO(C0-C4), ENTRE OTROS R5 ES H O ALQUILO(C1-C8) n ES 1 O 2. SON COMPUESTOS PREFERIDOS: 4-((CICLOPROPILMETILAMINO)-METIL)-6-(3-(METILAMINO)ACETIDIN-1-IL)PIRIMIDIN-2-AMINA 4-((2-ADAMANTILAMINO)METIL)-6-(3-(METILAMINO)ACETIDIN-1-IL)PIRIMIDIN-2-AMINA 4-(((2,2
