A misting device with quick release interchangeable cartridge is disclosed for atomizing and discharging a composition as a mist for topical application of the composition to the body or diffusing the composition into the ambient air. The cartridge quickly loads and unloads into an interior chamber of the container through a quick release coupling mechanism. The coupling mechanism may create a friction fit engagement. An atomizer atomizes the composition. A base maintains the container in an upright position for formulation of the composition in the cavity of the cartridge.