Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders

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专利权人:

The Regents of the University of California

发明人:

Hao Qian,Xiang-Dong Fu

申请号：

GB202017804

公开号：

GB2588307A

申请日:

2019.04.11

申请国别(地区):

GB

年份:

2021

代理人:

摘要：

Provided herein is a method of reprogramming a non-neuronal cell to a neuron. Aspects of the present disclosure relate to using cell reprogramming agent suppresses the expression or activity of PTB to convert a non-neuronal cell into a neuron. Also provided herein is a method of treating neurodegenerative disease by reprogramming non-neuronal cells in vivo to functional neurons.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/