Robert J. Altenbach,Andrew Bogdan,Nicolas Desroy,Gregory A. Gfesser,Stephen N. Greszler,John R. Koenig,Philip R. Kym,Bo Liu,Marc J. Scanio,Xenia Searle,Xueqing Wang,Ming C. Yeung,Gang Zhao
申请号:
US15723896
公开号:
US10399940B2
申请日:
2017.10.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention discloses compounds of Formula (I)wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.