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DEUTERATED CFTR MODULATORS AND METHODS OF USE
专利权人:
GALAPAGOS NV;ABBVIE S.À.R.L.
发明人:
Vincent S. Chan,Philip R. Kym,Shashank Shekhar,Xueqing Wang
申请号:
US16471762
公开号:
US20200123137A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention discloses compounds of Formula (I)wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, A, R19, R20, and R21 are as defined herein. The present invention relates to deuterated compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
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