ALTENBACH, ROBERT J.,BOGDAN, ANDREW,DESROY, NICOLAS,GFESSER, GREGORY A.,GRESZLER, STEPHEN N.,KOENIG, JOHN R.,KYM, PHILIP R.,LIU, BO,SCANIO, MARC J.,SEARLE, XENIA,WANG, XUEQING,YEUNG, MING C.,ZHAO, GAN
申请号:
CA3039647
公开号:
CA3039647A1
申请日:
2017.10.04
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.