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Envase que contiene una solución de fármaco con contenido reducido de oxígeno disuelto
专利权人:
OTSUKA PHARMACEUTICAL FACTORY; INC.
发明人:
SUMIYOSHI, NOBUAKI,TATEISHI, ISAMU,MORI, HITOSHI,MORIMOTO, YASUSHI
申请号:
ES07830562
公开号:
ES2543420T3
申请日:
2007.10.25
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
A package containing drug solution with reduced dissolved oxygen content, comprising a container for drug solution (15) formed of a plastic material having an oxygen permeability of not less than 200 cm3 / m2⋅ 24 atm h⋅ at a temperature of 25 ° C at a humidity of 60% RH at 12 hours after a sterilization process steam or a sterilizing process with hot water and having an oxygen permeability at steady state no greater than 100 cm3 / m2 ⋅ 24 atm at a temperature of 25 ° C at a humidity of 60% RH h⋅ and a drug solution contained and sealed in the drug solution container (15) wherein the drug solution contained and sealed in the container for drug solution (15) was subjected to sterilization by steam or the sterilization process with hot water, and to a deoxidation process for reducing a dissolved oxygen concentration of the drug solution to no more than 2 ppm when the oxygen permeability of the plastic material reaches the steady state level after the steam sterilization process or the sterilization process with hot water and wherein the container for drug solution (15) includes a plurality of container portions (19), (20) and (21) isolated from each other by a removable partition (18) or (22), wherein a solution containing amino acid is contained in a portion of the container (19) or (20), and a saccharide solution is contained in another portion of the container (19) or (20).Un envase que contiene solución de fármaco con un contenido reducido de oxígeno disuelto, que comprende un recipiente para solución de fármaco (15) formado de un material de plástico que tiene una permeabilidad al oxígeno no menor de 200 cm3/m2&sdot 24 h&sdot atm a una temperatura de 25 ºC a una humedad del 60 % HR a las 12 horas después de un proceso de esterilización con vapor o un proceso de esterilización con agua caliente y que tiene una permeabilidad al oxígeno en estado estacionario no mayor de 100 cm3/m2&sdot 24 h&sdot atm a una temperatura de 25 ºC a una humedad del 60 % HR y una solución
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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