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REŽIM DOZIRANJA KOD PRIMJENE DVOJNO SPECIFIČNOG PROTUTIJELA CD19XCD3
专利权人:
Amgen Research (Munich) GmbH
发明人:
NAGORSEN, Dirk,KUFER, Peter,ZUGMAIER, Gerhard,BAEUERLE, Patrick
申请号:
MEP30117
公开号:
ME02947B
申请日:
2010.10.27
申请国别(地区):
ME
年份:
2018
代理人:
摘要:
Provided herein is a method for assessing the risk of potential adverse effects for a human patient mediated by the administration of a CD19.times.CD3 bispecific antibody to said patient comprising determining the ratio of B cells to T cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient.
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